1. Preheat your oven to 350°F (175°C) and gather all your ingredients to prepare for cooking.
2. Prepare the crust by either using a pre-made crust and letting it come to room temperature or making your own homemade crust, placing it in a 9-inch pie dish.
3. In a medium-sized bowl, mix together the diced ham, cream cheese, and cheddar cheese until combined.
4. Add the chopped green onion, hot sauce, Worcestershire sauce, and optional sour cream to the mixture and stir until all the ingredients are blended evenly.
5. Pour the filling mixture into the prepared crust, spreading it out evenly with a spatula to ensure it’s well distributed.
6. Place the quiche in the preheated oven and bake for approximately 30-40 minutes, or until the filling is set and the top turns golden brown.
7. Remove the quiche from the oven when done and allow it to cool for at least 10 minutes. This resting period helps the flavors meld and makes it easier to slice.
8. Slice and serve the Mississippi Sin Quiche warm or at room temperature, either as a standalone dish or paired with your choice of sides.